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Transcript Both prediabetes and type 2 diabetes are caused by insulin resistance. Insulin resistance is now accepted to be closely associated with the accumulation of fat within our muscle cells.
This fat toxicity inside of our muscles is a major factor in the cause of insulin resistance and Type 2 diabetes, as it interferes with the action of insulin.
But this insulin resistance in our muscles starts years before diabetes is diagnosed. This is a graph of fasting blood sugars in the 13 years prior to the onset of diabetes.
Insulin resistance starts over a decade before diabetes is actually diagnosed, as blood sugar levels slowly start creeping up. What could underlie this relatively rapid failure of insulin secretion?
At first, the pancreas pumps out more and more insulin, trying to overcome fat-induced insulin resistance in the muscles, and high insulin levels can lead to the accumulation of fat in the liver, called fatty liver disease. Before diagnosis of type 2 diabetes, there is a long silent scream from the liver.
Normally, the liver is constantly producing blood sugar to keep our brain alive between meals.
But filled with fat, the liver becomes insulin resistant like our muscles do. So the pancreas pumps out even more insulin to deal with the high sugars, and our liver gets fatter and fatter.
Fatty muscles, in the context of too many calories, leads to a fatty liver, which leads to an even fattier liver.
This is all still before we have diabetes, but then the next vicious cycle starts. Fatty liver can be deadly. So now we know how diabetes develops. Fatty muscles lead to a fatty liver, which leads to a fatty pancreas. It is now clear that type 2 diabetes is a condition of excess fat inside our organs.
The only thing that was keeping us from diabetes, from unchecked skyrocketing blood sugar, is that the pancreas was working overtime pumping out extra insulin to overcome insulin resistance. Unable to then overcome the resistance, blood sugar levels go up and up and we have type 2 diabetes.
This has implications for cancer as well. It all traces back to fat getting into our muscle cells, causing insulin resistance.
Fat from our stomach, or fat going into our stomach. Now it should make sense why the American Diabetes Association recommends reduced intake of dietary fat as a strategy for reducing the risk for developing diabetes. To see any graphs, charts, graphics, images, and quotes to which Dr.
Greger may be referring, watch the above video. Please consider volunteering to help out on the site.Although payments from device manufacturers were strongly associated with defibrillator selection, rates of in-hospital complications and death were similar.
It looks like you've lost connection to our server. Please check your internet connection or reload this page. ← A Case of Racism-Induced Hypertension.
My BP goes up just thinking about modern American meds. I was poisoned by statins in , and it took out my Achilles tendons. I know because I spent 3 months in drug rehabilitation with them I would love to trade all the pain medication in the world . Household in-depth interviews were conducted to gather additional and detailed data concerning the explanatory model for mental distress in Zambia.
Eight eligible health professionals working in a mental institution were interviewed at their respective public health facilities. They call it a silent killer. I could be talking to you right. An In-Depth Analysis of the Modern World Silent Killer "Hypertension" PAGES 1. WORDS View Full Essay.
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Normal levels of both systolic and diastolic blood pressure are particularly important for the efficient function of vital organs such as the heart, brain and kidneys and for overall health and well-being.