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Upper airway obstruction surgery. Brachycephalic airway obstructive syndrome.
Brachycephalic airway obstruction syndrome — a review of cases. Animal Welfare8: This tendency is obvious among old and modem lap dogs. Dickie, Tobias Schwarz, Martin Sullivan. Textbook of Small Animal Surgery, 3d Ed.
Alex Gough, Alison Thomas. Cavalier King Charles spaniels, Cocker spaniels, Bulldogs, and Boxers were over-represented compared to the population of dogs having MR imaging. The most common appearance of material in the middle ear was isointense in T1-weighted images and hyperintense in T2-weighted images.
There was no apparent correlation between the signal characteristics of the material and the diagnosis. Enhanced signal after gadolinium administration was observed affecting the lining of the bulla in dogs with otitis media and in dogs with unrelated neurologic conditions.
In dogs without clinical signs of otitis media, finding an increased signal in the middle ear during MR imaging may reflect subclinical otitis media or fluid accumulation unrelated to inflammation. Brachycephalic dogs may be predisposed to this condition. Doxey S, Boswood A.
Daniel Brockman and David Holt, eds. March ; 47 3: Laryngeal collapse was present in 34 of 64 53 per cent dogs. Laryngeal collapse is relatively common in dogs presented for surgical correction of brachycephalic airway obstructive disease. Dogs with severe laryngeal collapse often respond well to surgery.
Clinical signs rarely resolve completely following surgery. May 1,9: Surgical treatment of brachycephalic syndrome in dogs appeared to be associated with a favorable long-term outcome, regardless of age, breed, specific diagnoses, or number and combinations of diagnoses.
New Knowledge, New Treatments. Different breeds are usually recognized as brachycephalic: However, some of the most interesting phenotypes are fixed in particular breeds and are therefore less tractable to genetic analysis using classical segregation-based mapping approaches.
We implemented an across breed mapping approach using a moderately dense SNP array, a low number of animals and breeds carefully selected for the phenotypes of interest to identify genetic variants responsible for breed-defining characteristics.
Using a modest number of affected 10—30 and control 20—60 samples from multiple breeds, the correct chromosomal assignment was identified in a proof of concept experiment using three previously defined loci; hyperuricosuria, white spotting and chondrodysplasia. Genome-wide association was performed in a similar manner for one of the most striking morphological traits in dogs: Although candidate gene approaches based on comparable phenotypes in mice and humans have been utilized for this trait, the causative gene has remained elusive using this method.
Samples from nine affected breeds and thirteen control breeds identified strong genome-wide associations for brachycephalic head type on Cfa 1. Two independent datasets identified the same genomic region. Levels of relative heterozygosity in the associated region indicate that it has been subjected to a selective sweep, consistent with it being a breed defining morphological characteristic.
Genotyping additional dogs in the region confirmed the association. To date, the genetic structure of dog breeds has primarily been exploited for genome wide association for segregating traits.Communication and quality management between these third parties and the coal mine tend to be ad hoc; for example, via email or a spreadsheet.
This information is then re-input into the coal mine’s internal systems. Installing a control system that would both support the management and provide information needed in order to make decisions.
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management control system - a case study of fci Approaches to studying performance in management control systems MCS in. 4 Management control system in Case Company. Studies during the last 25 years have showed this phenomenon.